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Erlotinib-induced autophagy in epidermal growth factor receptor mutated non-small cell lung cancer.

Identifieur interne : 001115 ( Main/Exploration ); précédent : 001114; suivant : 001116

Erlotinib-induced autophagy in epidermal growth factor receptor mutated non-small cell lung cancer.

Auteurs : Yuan-Yuan Li ; Sze-Kwan Lam ; Judith Choi-Wo Mak ; Chun-Yan Zheng ; James Chung-Man Ho [Hong Kong]

Source :

RBID : pubmed:23769318

Descripteurs français

English descriptors

Abstract

Erlotinib is a commonly used tyrosine kinase inhibitor (TKI) in non-small cell lung cancer (NSCLC). Autophagy is a catabolic process in response to stress and deprivation of nutrients. This study aims to investigate whether autophagy confers acquired resistance to erlotinib treatment in NSCLC.

DOI: 10.1016/j.lungcan.2013.05.012
PubMed: 23769318


Affiliations:


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<name sortKey="Mak, Judith Choi Wo" sort="Mak, Judith Choi Wo" uniqKey="Mak J" first="Judith Choi-Wo" last="Mak">Judith Choi-Wo Mak</name>
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